BDBM50465336 CHEMBL4284275

SMILES COC1NC(=O)c2c1c1c3ccccc3[nH]c1c1[nH]c3ccc(O)cc3c21

InChI Key InChIKey=LLNDFPNAHYUNPF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50465336   

TargetRho-associated protein kinase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50465336(CHEMBL4284275)
Affinity DataIC50: 910nMAssay Description:Inhibition of ROCK2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50465336(CHEMBL4284275)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ASK1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50465336(CHEMBL4284275)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PKCalpha (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50465336(CHEMBL4284275)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of PKCtheta (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50465336(CHEMBL4284275)
Affinity DataIC50: 320nMAssay Description:Inhibition of N-terminal His10-StrepII tagged human ROCK2 catalytic domain (1 to 553 residues) expressed in Sf9 insect cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed