BDBM50465331 CHEMBL4294912
SMILES Oc1ccc2[nH]c3c4[nH]c5ccccc5c4c4CNC(=O)c4c3c2c1
InChI Key InChIKey=GXZFDXZCJALHRF-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50465331
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of PKCalpha (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of ROCK2 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of ASK1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibition of PKCtheta (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of N-terminal His10-StrepII tagged human ROCK2 catalytic domain (1 to 553 residues) expressed in Sf9 insect cells by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 923nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Inhibition of PKCdelta (unknown origin)More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Zhejiang University
Curated by ChEMBL
Zhejiang University
Curated by ChEMBL
Affinity DataIC50: 139nMAssay Description:Inhibition of IKKbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 308nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 944nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair