BDBM50465289 CHEMBL4276933

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2ncc(C)c(=O)n2c1

InChI Key InChIKey=XUEJBBRTXBMNEU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465289   

LigandPNGBDBM50465289(CHEMBL4276933)
Affinity DataIC50: 28nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465289(CHEMBL4276933)
Affinity DataIC50: 119nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed