BDBM50465280 CHEMBL4287809

SMILES COc1ncc(cc1NS(=O)(=O)c1ccccc1F)-c1ccc2nccc(=O)n2c1

InChI Key InChIKey=QPYFGBHNBPDOFU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465280   

TargetSerine/threonine-protein kinase mTOR(Human)
Wuxi Apptec (Shanghai) Co.

Curated by ChEMBL
LigandPNGBDBM50465280(CHEMBL4287809)
Affinity DataIC50: 400nMAssay Description:Inhibition of mTOR in human MCF7 cells assessed as reduction in P70S6K phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
LigandPNGBDBM50465280(CHEMBL4287809)
Affinity DataIC50: 141nMAssay Description:Inhibition of PI3Kalpha in human MCF7 cells assessed as reduction in AKT phosphorylation after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed