BDBM50465214 CHEMBL4286062

SMILES C[C@@H](CC(=O)N1CCC(O)(Cn2cnc3c(-c4ccc(CN)cc4)n(C)nc3c2=O)CC1)c1ccccc1

InChI Key InChIKey=DGHAUZFDWIZFRM-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50465214   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465214(CHEMBL4286062)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of USP7 (unknown origin) by biochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465214(CHEMBL4286062)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human USP7 using Ub-Rho110 as substrate by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465214(CHEMBL4286062)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human USP7 using Ub-Rho110 as substrate by fluorescence based SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
Almac Discovery

Curated by ChEMBL
LigandPNGBDBM50465214(CHEMBL4286062)
Affinity DataKd:  4.71E+5nMAssay Description:Inhibition of human USP7 using Ub-Rho110 as substrate assessed as dissociation constant by fluorescence based SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed