BDBM50465108 CHEMBL4277543

SMILES CC(C)(N)C12CC3CC(CC(C3)C1)C2

InChI Key

Data  2 IC50  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50465108   

TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)
Affinity DataKd:  130nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel by isothermal calorimetric titrationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)
Affinity DataKd:  4.44E+5nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 M2 proton channel S31N mutant expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes assessed as blockade of inward currents at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes assessed as blockade of inward currents at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (A/Udorn/307/1972(H3N2)))
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to Influenza A virus A/Udorn/72 wild-type M2 proton channel expressed in Xenopus laevis oocytes at pH 5.5 by two-electrode voltage c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMatrix protein 2(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
National and Kapodistrian University of Athens

Curated by ChEMBL
LigandPNGBDBM50465108(CHEMBL4277543)
Affinity DataKd:  130nMAssay Description:Binding affinity to C-terminal amidated influenza A virus A/Udorn/72 (H3N2) M2 transmembrane domain (22 to 46 residues) in DPC micelles at pH 8 asses...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed