BDBM50465079 CHEMBL4290214

SMILES [H][C@]12CC[C@]([H])(CN(C1)c1nnc(C)o1)[C@H]2Nc1nc2N(CC(C)(C)c2c(NC)n1)c1ccc(F)cc1

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465079   

TargetPresenilin-1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50465079(CHEMBL4290214)
Affinity DataEC50:  34nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as reduction in amyloid beta (1 to 42) production after 60 mins by cell based AlphaLisa assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed