BDBM50465051 CHEMBL4285950

SMILES CC1(C)OB(OC1(C)C)c1ccc(CONC(=O)\C=C\c2cccc(c2)S(=O)(=O)Nc2ccccc2)cc1

InChI Key InChIKey=KYZYBMIBACBSKE-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50465051   

TargetHistone deacetylase 8(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50465051(CHEMBL4285950)
Affinity DataEC50:  3.41E+5nMAssay Description:Inhibition of human HDAC8 using RHK(Ac)K(Ac)AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50465051(CHEMBL4285950)
Affinity DataEC50:  2.02E+4nMAssay Description:Inhibition of human HDAC6 using RHKK(Ac)AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Xavier University of Louisiana

Curated by ChEMBL
LigandPNGBDBM50465051(CHEMBL4285950)
Affinity DataEC50:  350nMAssay Description:Inhibition of HDAC in human cell lysates using fluoro-substrate peptide/fluoro-deacetylated peptide as substrate incubated for 20 mins measured at 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed