BDBM50465001 CHEMBL4283606

SMILES COc1ccc(CCNC(=O)c2cnc(SC)nc2N2CCOCC2)cc1OC

InChI Key InChIKey=NULJNWINBNQZPW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50465001   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50465001(CHEMBL4283606)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50465001(CHEMBL4283606)
Affinity DataIC50: 61nMAssay Description:Inhibition of recombinant full length human N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50465001(CHEMBL4283606)
Affinity DataIC50: 284nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4A4 (2 to 886 residues) expressed in baculovirus infected Sf9 cells using cAMP as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50465001(CHEMBL4283606)
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D7 (2 to 748 residues) expressed in baculovirus infected Sf9 cells using cAMP as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50465001(CHEMBL4283606)
Affinity DataIC50: 326nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged PDE4C1 expressed in baculovirus infected Sf9 cells using cAMP as substrate after 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50465001(CHEMBL4283606)
Affinity DataIC50: 659nMAssay Description:Inhibition of PDE11A (unknown origin) using cAMP as substrate after 1 hr by LANCE TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed