BDBM50464966 CHEMBL4294367

SMILES CC(O)[C@@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1

InChI Key InChIKey=AILUPPFPYNWHMY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50464966   

TargetProteasome subunit beta type-8(Human)
University of Rennes 1

Curated by ChEMBL
LigandPNGBDBM50464966(CHEMBL4294367)
Affinity DataIC50: 572nMAssay Description:Inhibition of human 20S immunoproteasome beta-5 using Suc-LLVY-AMC as substrate incubated for 15 mins measured for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Rennes 1

Curated by ChEMBL
LigandPNGBDBM50464966(CHEMBL4294367)
Affinity DataIC50: 880nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5 using Suc-LLVY-AMC as substrate incubated for 15 mins measured for 45 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-9(Human)
University of Rennes 1

Curated by ChEMBL
LigandPNGBDBM50464966(CHEMBL4294367)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of human 20S immunoproteasome beta-1 using Ac-PAL-AMC as substrate incubated for 15 mins measured for 45 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed