BDBM50464890 CHEMBL4277101

SMILES [H][C@]12C[C@]([H])(C=C1)[C@@]1([H])C(=O)N(CCCCN3CCN(CC3)c3cccc4sccc34)C(=O)[C@@]21[H]

InChI Key InChIKey=KVJXXDNXTCGJKY-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50464890   

TargetAlpha-1A adrenergic receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464890(CHEMBL4277101)
Affinity DataIC50: 178nMAssay Description:Antagonist activity at adrenergic alpha1A receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464890(CHEMBL4277101)
Affinity DataIC50: 6.40nMAssay Description:Antagonist activity at dopamine D2 receptor (unknown origin) after 60 mins by Ultra lance cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464890(CHEMBL4277101)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at 5-HT1A receptor (unknown origin) after 60 mins by Ultra lance cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464890(CHEMBL4277101)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464890(CHEMBL4277101)
Affinity DataIC50: 341nMAssay Description:Antagonist activity at 5-HT2C receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464890(CHEMBL4277101)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at M3 receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464890(CHEMBL4277101)
Affinity DataIC50: 7.85E+3nMAssay Description:Inhibition of human ERG by auomated patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50464890(CHEMBL4277101)
Affinity DataIC50: 195nMAssay Description:Antagonist activity at histamine H1 receptor (unknown origin) after 10 mins by calcium 5 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed