BDBM50464816 CHEMBL4285001

SMILES Nc1ccccc1NC(=O)c1ccc(CNC(=O)OCc2ccc(OCCOc3no[n+]([O-])c3S(=O)(=O)c3ccccc3)nc2)cc1

InChI Key InChIKey=CEULGBOLQRVNEE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50464816   

TargetHistone deacetylase 3(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50464816(CHEMBL4285001)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of human FLAG-tagged HDAC3 expressed in HEK293T cells using acetylated lysine side chain as substrate after 1 hr by colorimetric detection...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50464816(CHEMBL4285001)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human FLAG-tagged HDAC1 expressed in HEK293T cells using acetylated lysine side chain as substrate after 1 hr by colorimetric detection...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50464816(CHEMBL4285001)
Affinity DataIC50: 370nMAssay Description:Inhibition of FLAG-tagged HDAC2 (unknown origin) expressed in HEK293T cells using acetylated lysine side chain as substrate after 1 hr by colorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50464816(CHEMBL4285001)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50464816(CHEMBL4285001)
Affinity DataIC50: 370nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50464816(CHEMBL4285001)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed