BDBM50464815 CHEMBL4281580

SMILES CN(CCCCC(CO[N+]([O-])=O)O[N+]([O-])=O)Cc1ccc(COC(=O)NCc2ccc(cc2)C(=O)Nc2ccccc2N)cn1

InChI Key InChIKey=CIOORWDADMZRRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50464815   

TargetHistone deacetylase 2(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50464815(CHEMBL4281580)
Affinity DataIC50: 390nMAssay Description:Inhibition of FLAG-tagged HDAC2 (unknown origin) expressed in HEK293T cells using acetylated lysine side chain as substrate after 1 hr by colorimetri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50464815(CHEMBL4281580)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human FLAG-tagged HDAC1 expressed in HEK293T cells using acetylated lysine side chain as substrate after 1 hr by colorimetric detection...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Goethe University

Curated by ChEMBL
LigandPNGBDBM50464815(CHEMBL4281580)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human FLAG-tagged HDAC3 expressed in HEK293T cells using acetylated lysine side chain as substrate after 1 hr by colorimetric detection...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed