BDBM50464767 Chalcomoracin

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])ccc(-[#6](=O)-[#6@@H]-2-[#6@H](-[#6]-[#6](-[#6])=[#6]-[#6@@H]-2-c2c(-[#8])cc(cc2-[#8])-c2cc3ccc(-[#8])cc3o2)-c2ccc(-[#8])cc2-[#8])c1-[#8]

InChI Key InChIKey=GEGQKWJGTWMSGB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50464767   

TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50464767(Chalcomoracin)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpB using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50464767(Chalcomoracin)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpB using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50464767(Chalcomoracin)
Affinity DataIC50: 7.29E+3nMAssay Description:Inhibition of LYP (unknown origin) using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition measured every ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50464767(Chalcomoracin)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 12(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50464767(Chalcomoracin)
Affinity DataIC50: 8.52E+3nMAssay Description:Inhibition of PTP-PEST (unknown origin) using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition measured e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50464767(Chalcomoracin)
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of human PTP1B using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition measured every minute fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50464767(Chalcomoracin)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of Staphylococcus aureus FabI assessed as inhibition at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed