BDBM50464671 CHEMBL3621615

SMILES Nc1nnc(NCc2c(Cl)cccc2Oc2ccccc2)[nH]1

InChI Key InChIKey=KRCUOVZXEJFNAE-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50464671   

TargetLysine-specific histone demethylase 1A(Human)
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50464671(CHEMBL3621615)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50464671(CHEMBL3621615)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MAOA (unknown origin) by luminiscent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50464671(CHEMBL3621615)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MAOB (unknown origin) by luminiscent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetREST corepressor 1(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50464671(CHEMBL3621615)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of recombinant LSD1/CoREST (unknown origin) assessed as residual activity for 30 mins to 4 hrs by fluorescence based assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetREST corepressor 1(Human)
Medical University of South Carolina

Curated by ChEMBL
LigandPNGBDBM50464671(CHEMBL3621615)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant human LSD1/CoREST using 10-acetyl-3,7-dihydroxyphenoxazine as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetSpermine oxidase(Human)
Dart Neuroscience

Curated by ChEMBL
LigandPNGBDBM50464671(CHEMBL3621615)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human SMOXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50464671(CHEMBL3621615)
Affinity DataKi:  2.20E+3nMAssay Description:Competitive inhibition of LSD1 (unknown origin) incubated for 30 mins using H3K4me2 substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed