BDBM50464604 CHEMBL4283885

SMILES CC(C)N1CCN(CC1)c1ccc(Nc2ncc(F)c(n2)-c2cc3c(N=C(C)C33CCCC3)c(F)c2)nc1

InChI Key InChIKey=XVZGPEMMXNNRMV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50464604   

TargetCyclin-A2/Cyclin-dependent kinase 1(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50464604(CHEMBL4283885)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of CDK1/Cyclin-A2 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50464604(CHEMBL4283885)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK6/Cyclin-D3 (unknown origin) using histoneH1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50464604(CHEMBL4283885)
Affinity DataIC50: 78nMAssay Description:Inhibition of CDK4/Cyclin-D1 (unknown origin) using histone-H1 as substrate after 90 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed