BDBM50464553 CHEMBL4283995::US10889552, Compound 14f

SMILES COc1cc(CN(C)C(=O)c2cc(Cl)c(O)cc2O)cc(OC)c1OC

InChI Key InChIKey=VUGIZZANDHBHQG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50464553   

TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50464553(CHEMBL4283995 | US10889552, Compound 14f)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FITC-geldanamycin binding to N-terminal domain of recombinant full-length HSP90alpha (unknown origin) after 16 hrs by fluorescence pola...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandPNGBDBM50464553(CHEMBL4283995 | US10889552, Compound 14f)
Affinity DataIC50: 1.46E+3nMAssay Description:Endonuclease activity assays were carried out in Black Costar 96-well plates. Each well contained a total volume of 100 μL comprised of: buffer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2021
Entry Details
Go to US Patent