BDBM50464538 CHEMBL4289577

SMILES Fc1ccc(cc1)-n1c2ncccc2cc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c1=O

InChI Key InChIKey=IXULLLZCNUKGBJ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50464538   

TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50464538(CHEMBL4289577)
Affinity DataIC50: 633nMAssay Description:Inhibition of EGFR (unknown origin) using poly(Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50464538(CHEMBL4289577)
Affinity DataIC50: 685nMAssay Description:Inhibition of cKIT (unknown origin) using poly(Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50464538(CHEMBL4289577)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of cMET (unknown origin) using poly(Glu,Tyr) 4:1 substrate after 30 mins by HTFR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50464538(CHEMBL4289577)
Affinity DataIC50: 152nMAssay Description:Inhibition of VEGFR2 (unknown origin) using poly(Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50464538(CHEMBL4289577)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using poly(Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50464538(CHEMBL4289577)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Flt-3 (unknown origin) using poly(Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed