BDBM50464484 CHEMBL4290910

SMILES [O-][N+](=O)c1cc(c(cc1F)-c1ccc(COc2cccc(c2)C(F)(F)F)cc1)[N+]([O-])=O

InChI Key InChIKey=JBAZNFHIDNQNMZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464484   

TargetProstaglandin E synthase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50464484(CHEMBL4290910)
Affinity DataIC50: 260nMAssay Description:Inhibition of mPGES1 in IL-1beta-stimulated human A549 cell microsomes using PGH2 as substrate assessed as reduction in PGE2 production preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed