BDBM50464219 CHEMBL4238147

SMILES C[C@@H](Nc1nc(Nc2ccc(F)c(Cl)c2)nc2c(CCN)cccc12)C1CC1

InChI Key InChIKey=APMIWCHVZOOHNY-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464219   

TargetSon of sevenless homolog 1(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50464219(CHEMBL4238147)
Affinity DataEC50:  2.70E+3nMAssay Description:Activation of SOS1 in human HeLa cells assessed as increase in RAS-GTP levels after 30 mins by pull-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed