BDBM50464043 CHEMBL4237252

SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)Oc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=DGMLYRGMJHVKNC-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50464043   

TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50464043(CHEMBL4237252)
Affinity DataEC50:  120nMAssay Description:Transactivation of GAL4-tagged human PPARgamma LBD expressed in human HepG2 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50464043(CHEMBL4237252)
Affinity DataEC50:  2.85E+3nMAssay Description:Synergistic agonist activity at human PPARgamma LBD assessed as biotin-labeled PGC1alpha (130 to 154 residues) co-activator recruitment after 1 hr in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50464043(CHEMBL4237252)
Affinity DataEC50:  3.69E+3nMAssay Description:Synergistic agonist activity at human PPARgamma LBD assessed as biotin-labeled PGC1alpha (130 to 154 residues) co-activator recruitment after 1 hr in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50464043(CHEMBL4237252)
Affinity DataEC50:  9.78E+3nMAssay Description:Synergistic agonist activity at human PPARgamma LBD assessed as biotin-labeled PGC1alpha (130 to 154 residues) co-activator recruitment after 1 hr in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50464043(CHEMBL4237252)
Affinity DataEC50:  1.05E+3nMAssay Description:Transactivation of GAL4-tagged human PPARalpha LBD expressed in human HepG2 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed