BDBM50463989 CHEMBL4249547

SMILES COc1ccccc1N1CCN(Cc2ccc(OCc3cn(CCOCCOCCOCCNC(=O)COc4cncc(c4)C#Cc4csc(C)n4)nn3)c(OC)c2)CC1

InChI Key InChIKey=SIMRHOCKDXANLH-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463989   

TargetMetabotropic glutamate receptor 5(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463989(CHEMBL4249547)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at mGluR5 (unknown origin) expressed in HEK293T cells assessed as inhibition of L-Glu-induced MAPK phosphorylation preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463989(CHEMBL4249547)
Affinity DataKi:  251nMAssay Description:Displacement of [3H]-Raclopride from recombinant human dopamine D2 receptor expressed in HEK293T cell membranes co-expressing mGluR5a (unknown origin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50463989(CHEMBL4249547)
Affinity DataKi:  438nMAssay Description:Displacement of [3H]-Raclopride from recombinant human dopamine D2 receptor expressed in HEK293T cell membranes after 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed