BDBM50463881 CHEMBL4240336

SMILES Oc1ccc(C=C2C(=O)NC(=S)N(C2=O)c2ccc(Br)cc2)cc1O

InChI Key InChIKey=DYDDQZHSRAXCDS-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50463881   

TargetLysine-specific histone demethylase 1A(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50463881(CHEMBL4240336)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to fluorescently labeled recombinant human LSD1 expressed in Escherichia coli by MST analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50463881(CHEMBL4240336)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of recombinant full length N-terminal FLAG-tagged human MAO-B expressed in baculovirus infected Sf9 insect cells using flag peptide as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50463881(CHEMBL4240336)
Affinity DataIC50: 7.25E+4nMAssay Description:Inhibition of recombinant full length N-terminal FLAG-tagged human MAO-A expressed in baculovirus infected Sf9 insect cells using flag peptide as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50463881(CHEMBL4240336)
Affinity DataIC50: 410nMAssay Description:Inhibition of N-terminal truncated recombinant human LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3 (1 to 21 residues) K4m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed