BDBM50463852 CHEMBL4246078

SMILES FC(F)(F)c1cccnc1[C@@H](NC(=O)c1ccc2cccnc2c1)c1ccccc1

InChI Key InChIKey=SJTMLURACBBWQI-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463852   

TargetTransient receptor potential cation channel subfamily M member 8(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50463852(CHEMBL4246078)Copy SMILESCopy InChI

Affinity DataIC50: 1.26E+3nMAssay Description:Antagonist activity at mouse TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/17/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetTransient receptor potential cation channel subfamily M member 8(Human)
TBA

Curated by ChEMBL

LigandBDBM50463852(CHEMBL4246078)Copy SMILESCopy InChI

Affinity DataIC50: 389nMAssay Description:Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/17/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL