BDBM50463850 CHEMBL4241349

SMILES OC(=O)c1ccc(nc1)C(=O)N[C@@H](c1ccc(OC(F)(F)F)c(F)c1)c1ncccc1F

InChI Key InChIKey=QEBYISWYMFIXOZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50463850   

LigandPNGBDBM50463850(CHEMBL4241349)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of TRPA1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463850(CHEMBL4241349)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at rat TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463850(CHEMBL4241349)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of TRPV1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463850(CHEMBL4241349)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of TRPV3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463850(CHEMBL4241349)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of TRPV4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463850(CHEMBL4241349)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed