BDBM50463848 CHEMBL4245611

SMILES Cc1ccc(cc1)[C@H](NC(=O)c1ccc2cccnc2c1)c1ncccc1C(F)(F)F

InChI Key InChIKey=JROKQADOWNXEPY-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463848   

TargetTransient receptor potential cation channel subfamily M member 8(Human)
TBA

Curated by ChEMBL

LigandBDBM50463848(CHEMBL4245611)Copy SMILESCopy InChI

Affinity DataIC50: 75nMAssay Description:Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/17/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetTransient receptor potential cation channel subfamily M member 8(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50463848(CHEMBL4245611)Copy SMILESCopy InChI

Affinity DataIC50: 143nMAssay Description:Antagonist activity at mouse TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/17/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL