BDBM50463847 CHEMBL4246499

SMILES FC(F)(F)c1cccnc1[C@H](Cc1ccccc1)NC(=O)c1ccc2cccnc2c1

InChI Key InChIKey=BINBGFMPJSQVDS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463847   

TargetTransient receptor potential cation channel subfamily M member 8(Human)
TBA

Curated by ChEMBL

LigandBDBM50463847(CHEMBL4246499)Copy SMILESCopy InChI

Affinity DataIC50: 1.14E+3nMAssay Description:Antagonist activity at human TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/17/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetTransient receptor potential cation channel subfamily M member 8(Mouse)
TBA

Curated by ChEMBL

LigandBDBM50463847(CHEMBL4246499)Copy SMILESCopy InChI

Affinity DataIC50: 2.05E+3nMAssay Description:Antagonist activity at mouse TRPM8 expressed in CHO cells assessed as inhibition of icilin-induced intracellular calcium levels preincubated for 2.5 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/17/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL