BDBM50463620 CHEMBL4240937

SMILES CCN1\C(C=Cc2ccccc12)=C1/C(=O)N(N=C1Nc1ccccc1)c1ccccc1

InChI Key InChIKey=LUUCQXGRDYPNRB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50463620   

TargetLysyl oxidase homolog 3(Human)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50463620(CHEMBL4240937)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human LOXL3 expressed in CHO cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProtein-lysine 6-oxidase(Human)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50463620(CHEMBL4240937)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of recombinant human LOX expressed in HEK293 cells using diaminopentane as substrate preincubated for 30 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50463620(CHEMBL4240937)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant LOXL2 (unknown origin) expressed in NS0 cells using diaminopentane as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 4(Human)
Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50463620(CHEMBL4240937)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human LOXL4 expressed in baculovirus infected insect cells using diaminopentane as substrate preincubated for 30 mins follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed