BDBM50463401 CHEMBL4242565

SMILES FC(F)Oc1ccc(NC(=O)N2CCN(CC2)c2ncnc3n(c(nc23)-c2ccccc2Cl)-c2ccc(Cl)cc2)cn1

InChI Key InChIKey=OOOVILGNZRHNSE-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463401   

TargetCannabinoid receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50463401(CHEMBL4242565)
Affinity DataEC50:  590nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in HEK293 cells co-expressing Galphaq16 assessed as inhibition of calcium mobilization after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50463401(CHEMBL4242565)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]-CP55940 from human CB1 receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Rti International

Curated by ChEMBL
LigandPNGBDBM50463401(CHEMBL4242565)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in HEK293 cell membranes after 1 hr by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed