BDBM50463394 CHEMBL4246563

SMILES C=CC(=O)Nc1ccc(cc1)-n1c2c(ccc1=O)oc1ccc(cc21)-c1cccnc1

InChI Key InChIKey=QHUBDROWGBQYIY-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50463394   

LigandPNGBDBM50463394(CHEMBL4246563)
Affinity DataIC50: 275nMAssay Description:Inhibition of recombinant human full length N-terminal His-tagged PI3K p110delta/p85alpha using lipid substrate after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463394(CHEMBL4246563)
Affinity DataIC50: 838nMAssay Description:Inhibition of recombinant full length human N-terminal His6-tagged PI3K p110beta/p85alpha expressed in baculovirus infected Sf21 cells using lipid su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463394(CHEMBL4246563)
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant full length human N-terminal His tagged BTK expressed in baculovirus infected Sf9 cells using poly (4:1 Glu, Tyr) as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463394(CHEMBL4246563)
Affinity DataIC50: 228nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362-end residues)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463394(CHEMBL4246563)
Affinity DataIC50: 254nMAssay Description:Inhibition of recombinant human full length His-tagged PI3K p110alpha/p85alpha expressed in baculovirus expression system using lipid substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463394(CHEMBL4246563)
Affinity DataIC50: 684nMAssay Description:Inhibition of recombinant human full length His-tagged PI3K p110gamma expressed in baculovirus expression system using lipid substrate after 60 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50463394(CHEMBL4246563)
Affinity DataIC50: 275nMAssay Description:Inhibition of PI3Kdelta (unknown origin) by ADP-gloassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50463394(CHEMBL4246563)
Affinity DataIC50: 254nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by ADP-gloassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50463394(CHEMBL4246563)
Affinity DataIC50: 838nMAssay Description:Inhibition of PI3Kbeta (unknown origin) by ADP-gloassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50463394(CHEMBL4246563)
Affinity DataIC50: 684nMAssay Description:Inhibition of PI3Kgamma (unknown origin) by ADP-gloassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463394(CHEMBL4246563)
Affinity DataIC50: 228nMAssay Description:Inhibition of mTOR (unknown origin) by ADP-gloassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed