BDBM50463393 CHEMBL4247514

SMILES COc1ccc(cn1)-c1ccc2oc3ccc(=O)n(-c4ccc(NC(=O)CN5CCN(C)CC5)cc4)c3c2c1

InChI Key InChIKey=OMPBTNPIOUMRRU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463393   

TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463393(CHEMBL4247514)
Affinity DataIC50: 139nMAssay Description:Inhibition of recombinant full length human N-terminal His tagged BTK expressed in baculovirus infected Sf9 cells using poly (4:1 Glu, Tyr) as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50463393(CHEMBL4247514)
Affinity DataIC50: 153nMAssay Description:Inhibition of BTK (unknown origin) by ADP-gloassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed