BDBM50463285 CHEMBL4241369

SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]51CC[C@@]2(OC)[C@](C)(C1)C(=O)c1ccc(cc1)C(F)(F)F)ccc3OC

InChI Key

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50463285   

TargetDelta-type opioid receptor(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50463285(CHEMBL4241369)
Affinity DataEC50:  1.76E+3nMAssay Description:Agonist activity at rat DOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding based liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50463285(CHEMBL4241369)
Affinity DataEC50:  165nMAssay Description:Agonist activity at rat MOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding based liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50463285(CHEMBL4241369)
Affinity DataEC50:  173nMAssay Description:Agonist activity at human KOR expressed in CHO cell membranes after 1 hr by [35S]GTPgammaS binding based liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50463285(CHEMBL4241369)
Affinity DataKi:  72nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in CHO cell membranes after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50463285(CHEMBL4241369)
Affinity DataKi:  81nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in CHO cell membranes after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50463285(CHEMBL4241369)
Affinity DataKi:  127nMAssay Description:Displacement of [3H]DPDPE from human DOR expressed in CHO cell membranes after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed