BDBM50463209 CHEMBL4249170

SMILES c1cnccc1C[C@@H](C(=O)O)N

InChI Key InChIKey=FQFVANSXYKWQOT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50463209   

TargetLarge neutral amino acids transporter small subunit 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50463209(CHEMBL4249170)
Affinity DataIC50: 1.00E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetLarge neutral amino acids transporter small subunit 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50463209(CHEMBL4249170)
Affinity DataIC50: 1.00E+5nMAssay Description:Cis-inhibition of human LAT1 expressed in TREx HEK293 cells assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 degC follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed