BDBM50463156 CHEMBL4250264

SMILES CCOC(=O)\C=C\[C@@H](O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)N1CCOCC1

InChI Key InChIKey=PQCJGLQDIOZNSL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50463156   

TargetCruzipain(Trypanosoma cruzi)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463156(CHEMBL4250264)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463156(CHEMBL4250264)
Affinity DataIC50: 2.45E+3nMAssay Description:Inhibition of human cathepsin L using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463156(CHEMBL4250264)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human cathepsin B using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463156(CHEMBL4250264)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed