BDBM50463151 CHEMBL4249696

SMILES CCOC(=O)\C=C\C(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)N1CCOCC1

InChI Key InChIKey=JRFCJBAMIBGKTB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50463151   

TargetCathepsin B(Human)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463151(CHEMBL4249696)
Affinity DataIC50: 140nMAssay Description:Inhibition of human cathepsin B using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463151(CHEMBL4249696)
Affinity DataIC50: 340nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463151(CHEMBL4249696)
Affinity DataIC50: 140nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463151(CHEMBL4249696)
Affinity DataIC50: 210nMAssay Description:Inhibition of human cathepsin L using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed