BDBM50463150 CHEMBL4246909

SMILES CCOC(=O)\C=C\[C@@H](O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=KFUZPOVRSYFYMN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50463150   

TargetProcathepsin L(Human)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463150(CHEMBL4246909)
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of human cathepsin L using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463150(CHEMBL4246909)
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCysteine proteinase falcipain 2a(malaria parasite P. falciparum)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463150(CHEMBL4246909)
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2 using Cbz-Phe-Arg-AMC as substrate measured for 15 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed