BDBM50463149 CHEMBL4248915

SMILES CCOC(=O)\C=C\C(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

InChI Key InChIKey=UUBYFYHAUYKPFR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50463149   

TargetCysteine proteinase falcipain 2a(malaria parasite P. falciparum)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463149(CHEMBL4248915)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2 using Cbz-Phe-Arg-AMC as substrate measured for 15 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463149(CHEMBL4248915)
Affinity DataIC50: 500nMAssay Description:Inhibition of human cathepsin L using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463149(CHEMBL4248915)
Affinity DataIC50: 800nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463149(CHEMBL4248915)
Affinity DataIC50: 630nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCathepsin B(Human)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463149(CHEMBL4248915)
Affinity DataIC50: 70nMAssay Description:Inhibition of human cathepsin B using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed