BDBM50463143 CHEMBL4245127

SMILES CCOC(=O)\C=C\C(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

InChI Key InChIKey=MEBPGJFXXVRICE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50463143   

TargetCathepsin B(Human)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463143(CHEMBL4245127)
Affinity DataIC50: 50nMAssay Description:Inhibition of human cathepsin B using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCysteine proteinase falcipain 2a(malaria parasite P. falciparum)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463143(CHEMBL4245127)
Affinity DataIC50: 580nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2 using Cbz-Phe-Arg-AMC as substrate measured for 15 mins by spectrofluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463143(CHEMBL4245127)
Affinity DataIC50: 145nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesain using Cbz-Phe-Arg-AMC as substrate measured for 30 mins by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463143(CHEMBL4245127)
Affinity DataIC50: 80nMAssay Description:Inhibition of Trypanosoma cruzi cruzainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463143(CHEMBL4245127)
Affinity DataIC50: 260nMAssay Description:Inhibition of human cathepsin L using Cbz-Phe-Arg-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Universitat Jaume I

Curated by ChEMBL
LigandPNGBDBM50463143(CHEMBL4245127)
Affinity DataIC50: 145nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed