BDBM50462929 CHEMBL4237546

SMILES Clc1cc(Cl)cc(c1)C(=O)NCCCN1CCN(CC1)c1ncccn1

InChI Key InChIKey=FJIIQQZRTHPVPO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50462929   

TargetSodium-dependent noradrenaline transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50462929(CHEMBL4237546)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NET expressed in HEK293 cells assessed as reduction in [3H]-NE uptake by micro beta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50462929(CHEMBL4237546)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SERT expressed in HEK293 cells assessed as reduction in [3H]5-HT uptake by micro beta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50462929(CHEMBL4237546)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DAT expressed in HEK293 cells assessed as reduction in [3H]-DA uptake by micro beta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed