BDBM50462731 CHEMBL4238200

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2ccc(OCCO[N+]([O-])=O)cc2)c1

InChI Key InChIKey=YNBLGAIFNAPXFU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462731   

TargetSodium/glucose cotransporter 2(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50462731(CHEMBL4238200)
Affinity DataIC50: 246nMAssay Description:Inhibition of human SGLT2 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50462731(CHEMBL4238200)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SGLT1 expressed in HEK293 cells assessed as decrease in [14C]-AMG uptake preincubated for 10 mins followed by [14C]-AMG addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed