BDBM50462721 CHEMBL4243822

SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(Nc2nc(-c3cnn(CCCCCCOc4ccccc4)c3)c3cc[nH]c3n2)cc1

InChI Key InChIKey=HTSKKSHDBBPAFS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50462721   

TargetHistone deacetylase 1(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50462721(CHEMBL4243822)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human HDAC1 using p53 (379 to 382 residues) derived fluorogenic peptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50462721(CHEMBL4243822)
Affinity DataIC50: 16nMAssay Description:Inhibition of human HDAC6 using p53 (379 to 382 residues) derived fluorogenic peptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
National University of Singapore

Curated by ChEMBL
LigandPNGBDBM50462721(CHEMBL4243822)
Affinity DataIC50: 19nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed