BDBM50462643 CHEMBL4246481

SMILES COC(Cc1nc(N2CCOC[C@@H]2C)c2ccc(nc2n1)-c1ccc(OC)c(CO)c1)OC

InChI Key InChIKey=QENAZHNQLZMAPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462643   

TargetSerine/threonine-protein kinase mTOR(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462643(CHEMBL4246481)
Affinity DataIC50: 29nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide substrate measured after 1 hr by Lance Ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462643(CHEMBL4246481)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 1 hr by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed