BDBM50462641 CHEMBL4246121

SMILES COc1ccc(cc1CO)-c1ccc2c(nc(nc2n1)C1=CCOCC1)N1CCOC[C@@H]1C

InChI Key InChIKey=PQSRXIWKDZAALQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462641   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462641(CHEMBL4246121)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate measured after 1 hr by Kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50462641(CHEMBL4246121)
Affinity DataIC50: 30nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide substrate measured after 1 hr by Lance Ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed