BDBM50462401 CHEMBL4243739

SMILES [H][C@@]12CC[C@@](O)(C#CC(=O)OCC3CCC#C\C=C/C#CC3)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]

InChI Key InChIKey=JGSWONLDXYWFKC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50462401   

TargetEstrogen receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50462401(CHEMBL4243739)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human estrogen receptor alpha expressed in HEK293 cells assessed as reduction in estrogen-induced transcriptional activation after 6 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50462401(CHEMBL4243739)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human estrogen receptor alpha expressed in human LNCAP cells assessed as reduction in estrogen-induced transcriptional activation after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50462401(CHEMBL4243739)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of human estrogen receptor alpha expressed in human MCF7 cells assessed as reduction in estrogen-induced transcriptional activation after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Punjabi University

Curated by ChEMBL
LigandPNGBDBM50462401(CHEMBL4243739)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human estrogen receptor alpha expressed in human MDA-MB-231 cells assessed as reduction in estrogen-induced transcriptional activation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed