BDBM50462184 CHEMBL4250674

SMILES CC(C)n1nc(C#Cc2cccc3cc(ncc23)-c2ccc(Cl)c(c2)C(F)(F)F)c2c(N)ncnc12

InChI Key InChIKey=GMHHKAPVIOBKKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50462184   

TargetSerine/threonine-protein kinase B-raf(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50462184(CHEMBL4250674)
Affinity DataIC50: 87nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) after 20 mins by immunoblotting assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50462184(CHEMBL4250674)
Affinity DataIC50: 22nMAssay Description:Inhibition of ABL (unknown origin) by phosphocellulose paper disk assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed