BDBM50462116 CHEMBL4250582

SMILES C[Si](O)(O)CCCCCCC(=O)Nc1ccccc1

InChI Key InChIKey=SYOJIQXYKCJISC-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50462116   

TargetHistone deacetylase 1(Human)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Ac-Leu-Gly-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
Csir-National Chemical Laboratory

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human recombinant HDAC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human recombinant HDAC6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant HDAC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant HDAC8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant HDAC10More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
Ghent University

Curated by ChEMBL
LigandPNGBDBM50462116(CHEMBL4250582)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of human recombinant HDAC11More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed