BDBM50462102 CHEMBL4240381

SMILES CC[C@H](C)[C@H](NC(=O)CN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(O)=O

InChI Key InChIKey=BLDLDULDJCSLSE-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50462102   

TargetMannan-binding lectin serine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50462102(CHEMBL4240381)
Affinity DataIC50: 40nMAssay Description:Inhibition of MASP-1-mediated C3 deposition in human serum after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMannan-binding lectin serine protease 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50462102(CHEMBL4240381)
Affinity DataIC50: 230nMAssay Description:Inhibition of MASP-2-mediated C4 deposition in human serum after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMannan-binding lectin serine protease 1(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50462102(CHEMBL4240381)
Affinity DataKi:  65nMAssay Description:Inhibition of MASP-1 (unknown origin) using Z-L-LysSBzl hydrochloride as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetMannan-binding lectin serine protease 2(Human)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50462102(CHEMBL4240381)
Affinity DataKi:  1.03E+3nMAssay Description:Inhibition of MASP-2 (unknown origin) using Z-L-LysSBzl hydrochloride as substrate preincubated for 1 hr followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed