BDBM50462048 CHEMBL4228991

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)N1C\C(=C/c2ccc(F)cc2)C(=O)\C(C1)=C\c1ccc(F)cc1)B(O)O

InChI Key InChIKey=HVWLSBSIMKMDFL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50462048   

TargetProteasome subunit beta type-2(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50462048(CHEMBL4228991)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of trypsin-like activity of 20S proteasome in human K562 cells using Z-LRRaminoluciferin as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50462048(CHEMBL4228991)
Affinity DataIC50: 835nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human K562 cells using Suc-LLVYaminoluciferin as substrate after 2 hrs by luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50462048(CHEMBL4228991)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of PGPH activity of 20S proteasome in human K562 cells using Z-nLPnLDaminoluciferin as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed