BDBM50462047 CHEMBL455159

SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(OC(=O)[C@@H](N)C(C)C)c(OC)c2)ccc1OC(=O)[C@@H](N)C(C)C

InChI Key InChIKey=RVFUPBDRJITFOE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50462047   

TargetProteasome subunit beta type-5(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50462047(CHEMBL455159)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human LNCAP cell extract using Suc-LLVYaminoluciferin as substrate after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50462047(CHEMBL455159)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human PC3 cell extract using Suc-LLVYaminoluciferin as substrate after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50462047(CHEMBL455159)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of chymotrypsin-like activity of 20S proteasome in human K562 cells using Suc-LLVYaminoluciferin as substrate after 2 hrs by luminescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed