BDBM50461911 CHEMBL4229033

SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ncc[nH]2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]2CSSC[C@H](NC(=O)CN)C(=O)N[C@@H](CSSC[C@H](NC1=O)C(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N2

InChI Key InChIKey=NXGWHVWTEAHKPX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50461911   

TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50461911(CHEMBL4229033)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human alpha9/alpha10 nACHR (1:1) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current measured for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50461911(CHEMBL4229033)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human alpha9 N154G mutant/alpha10 nACHR (3:1) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50461911(CHEMBL4229033)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of human alpha9/alpha10 nACHR (1:3) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current measured for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50461911(CHEMBL4229033)
Affinity DataIC50: 750nMAssay Description:Inhibition of human alpha9/alpha10 G154N mutant nACHR (1:3) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50461911(CHEMBL4229033)
Affinity DataIC50: 750nMAssay Description:Inhibition of human alpha9/alpha10 nACHR (3:1) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current measured for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor; alpha9/alpha10(Human)
Ocean University of China

Curated by ChEMBL
LigandPNGBDBM50461911(CHEMBL4229033)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of human alpha9 N154G mutant/alpha10 nACHR (1:3) expressed in Xenopus laevis oocyte assessed as inhibition of ACh induced channel current ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed